Sodium borohydride (NaBH4) is a versatile reducing agent used in a number of industrial processes. Major applications include organic and pharmaceutical synthesis, wastewater treatment, and paper pulp bleaching. Sodium borohydride plays such a significant role in organic synthesis. It is a good reducing agent which has stable performance and selective reduction. It can be used as the reducing agents of aldehydes, ketones and acid chlorides; also as foaming agent for plastic materials, hydrogenating agent of making dihydrostreptomycin, intermediate of making potassium borohydride, raw materials in synthesizing borane, as well as the treatment agent of paper industry and mercury-containing waste water.
Sodium borohydride provides organic chemists a very convenient and mild means for reduction of aldehydes and ketones. Before this, people usually use metal/alcohol approach to reduce carbonyl compound. Sodium borohydride enables the reduction of carbonyl of aldehydes and ketones under very mild conditions to produce primary alcohols and secondary alcohols. Reduction procedure is as below: First dissolve the substrate in a solvent (typically methanol or ethanol), then cool with an ice bath. Finally add sodium borohydride powder to the mixture until the reaction is completed. The reaction process can be monitored by thin layer chromatography. If the solvent is not an alcohol, we need to additionally supply methanol or ethanol along with the reaction. Sodium borohydride is a reducing agent with medium strength, and thus exhibiting good chemical selectivity. It only reduces active aldehyde and ketone carbonyl group, and does not react with the ester, amide.
Product Name: | Sodium borohydride |
Synonyms: | VenPure SF;SodiuM borohydride caplets (18 x 10 x 8 MM), 98%;SodiuM borohydride granular, 10-40 Mesh, 98%;SodiuM borohydride granular, 99.99% trace Metals basis;SodiuM borohydride powder, >=98.0%;SodiuM borohydride puruM p.a., >=96% (gas-voluMetric);SodiuM borohydride ReagentPlus(R), 99%;SodiuM borohydride solution 2.0 M in triethylene glycol diMethyl ether |
CAS NO: | 16940-66-2 |
EINECS: | 241-004-4 |
Molecular Formula: | BH4Na |
Molecular Weight: | 37.83 |
Melting Point: | >300 °C (dec.) (lit.) |
Boiling Point: | 500°C |
Density: | 1.035 g/mL at 25 °C |
Appearance: | White powder |
Storage: | Store at RT. |
Solubility: | Water Solubility 550 g/L (25 ºC) |
Applications: | Sodium borohydride (NaBH4) is a versatile reducing agent used in many industrial processes. Key applications include organic and pharmaceutical synthesis, wastewater treatment and pulp bleaching. Sodium borohydride plays such an important role in organic synthesis. It is an excellent reducing agent with stable performance and selective reduction. It is used as a reducing agent for aldehydes, ketones and acid chlorides; it is also used as a foaming agent for plastic materials, a hydrogenation agent for the manufacture of dihydrostreptomycin, an intermediate for the manufacture of potassium borohydride, a raw material for the synthesis of borane, and as a raw material for the paper industry and Treatment agent for mercury-containing wastewater. |
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